Nerve repair
Peripheral nerve portfolio
Our nerve portfolio consists of type I collagen conduits and wraps. They are designed to provide a protective layer around injured peripheral nerves and offer a resorbable and semi-permeable encasement to facilitate nerve repair.
Peripheral nerve repair
Nerve conduits and wraps provide an encasement for peripheral nerve injuries and protection of the neural environment. NeuroMatrix, Neuroflex, and NeuroMend are semi-permeable structures that allow diffusion of nutrients and neurotrophic factors into the conduit, but provide a barrier to larger, scar-forming cells.1,2
- Neuroflex is the only nerve conduit indicated for the treatment of symptomatic or painful neuromas and features corrugated walls allowing it to bend up to approximately 60 degrees without forming an occlusion3,4
- Designed to be an interface between the nerve and the sorrounding tissue to prevent the ingrowth of scar tissue
- Use of NeuroMatrix and Neuroflex removes the risk of donor-site morbidity, scarring and neuroma formation.5,6
- Use of a nerve conduit offers a tensionless repair option when direct suture is not possible
- NeuroMend allows for a 25% overlap to potentially eliminate the need for a running suture.
- NeuroMend offers a self-curling design to better match the dimensions of the nerve and provides the ability to wrap nerves from 2.0mm to 12.0mm in diameter.
- Expected to completely resorb in about 8 months after implantation.7,8
- Li ST. Peripheral Nerve Repair with Collagen Conduits. Clinical Materials 9 (1992) 195-200.
- The results of preclinical and in vitro studies may not be indicative of human clinical outcomes
- Li St., Yuen D., Jenssen JR., A semipermeable, Kink Resistant Type I Colalgen-based Nerve Guide for PNS Repair. Collagen Matrix, Inc. 2003.
- U.S. Patent #6,716,225, Implant Devices for Nerve Repair, 2004.
- Taras, John, Vipul Nanavati, and Pamela Steelman. “Nerve Conduits.” Journal of Hand Therapy 18.2 (2005): 191-97.
- Weber, Robert, Warren Breidenbach, Richard Brown, Michael Jabaley, and Daniel Mass. “A Randomized Prospective Study of Polyglycolic Acid Conduits for Digital Nerve Reconstruction in Humans.” Plastic and Reconstructive Surgery 106.5 (2000): 1036-045.
- The results of preclinical and in vitro studies may not be indicative of human clinical outcomes
- Animal study data on file at Collagen Matrix, Inc
Manufacturered by: Collagen Matrix, Inc. 15 Thornton Rd Oakland, NJ 07436
CP-AWI-12, 07-2017