Vitoss BA2X
Bioactive Bone Graft Substitute
A synthetic bone graft that has increased levels of bioactive glass compared to Vitoss BA, and has a unique porosity, structure, and chemistry to help drive 3D regeneration of bone
Now sold by VB Spine
Vitoss BA2X Bioactive Bone Graft Substitute
Vitoss BA2X contains increased levels of bioactive glass. In-vitro testing showed that it induced two times the deposition of calcium phosphate onto the surface of an implant while retaining the same handling properties.1
Highly porous calcium-phosphate (up to 90% porous)2 containing bioactive glass
Stable at physiological pH3 and resorbs during the natural remodeling process of bone4
The addition of bioactive glass helps create a surface favorable for osteoblast attachment5-11
Vitoss BA2X Foam Pack is stable in a fluid environment, can soak and hold bone marrow, and is moldable
Note: In-vitro bioactivity testing has not been evaluated in human clinical trials.
Image sourced from Vitoss BiModal Technical Sheet 5701-0096 Rev.00
References:
- Stryker Spine Test Report P/N 1000-2024R
- Stryker Spine Test Report P/N 1070-0008R
- Rey C, Combes C, Drouet C, Grossin D. (2011). Bioactive Ceramics - Physical Chemistry. In Ducheyne, Paul. Comprehensive Biomaterials. 1. Elsevier. pp. 187–281.
- Anker et al, Ultraporous Beta-Tricalcium Phosphate is Well Incorporated in Small Cavitary Defects. Clinical Orthopaedics and Related Research, 2005 May; 434: 251-7.
- Hench, L.L., Splinter, R.J., and Allen, W.C., Bonding Mechanisms at the Interface of Ceramic Prosthetic Materials. Journal of Biomedical Materials Research, 1971; 2(1): 117-141.
- Hench, L.L., Paschall, H.A., Direct Chemical Bond of Bioactive Glass-Ceramic Materials to Bone and Muscle. Journal of Biomedical Materials Research, 1973; 4: 25-42.
- Gross, U., The Interface of Various Glasses and Glass Ceramics with a Bony Implantation Bed. Journal of Biomedical Materials Research, 1985; 19: 251-271.
- Vrouwenvelder, W.C.A., Histological and Biochemical Evaluation of Osteoblasts Cultured on Bioactive Glass, Hydroxylapatite, Titanium Alloy, and Stainless Steel. Journal of Biomedical Materials Research, 1993 Apr; 27(4): 465-75.
- Sanders, D.M., Hench, L.L., Mechanisms of Glass Corrosion. Journal of American Ceramic Society.1973; 56(7): 373-377.
- Hench, L.L., Characterization of Glass Corrosion and Durability. Journal of Non-Crystalline Solids, 1975; 19: 27-39.
- Ogino, M., Hench, L.L., Formation of Calcium Phosphate Films on Silicate Glasses. Journal of Non-Crystalline Solids, 1980; 38 and 39: 673-678.
BIVIT-WB-4_Rev-1_16204
JR-GSNPS-SYK-1779850